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<t> Physiologically Based Pharmacokinetic </t> <t> (PBPK) </t> volatile organic compounds (VOCs) Model Comparison.
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Physiologically Based Pharmacokinetic (PBPK) volatile organic compounds (VOCs) Model Comparison.

Journal: International Journal of Molecular Sciences

Article Title: Development of a Human Physiologically Based Pharmacokinetic (PBPK) Toolkit for Environmental Pollutants

doi: 10.3390/ijms12117469

Figure Lengend Snippet: Physiologically Based Pharmacokinetic (PBPK) volatile organic compounds (VOCs) Model Comparison.

Article Snippet: The Agency for Toxic Substances and Disease Registry (ATSDR) has conducted translational research to develop a human PBPK model toolkit by recoding published PBPK models.

Techniques: Comparison

Comparison of Minimal Risk Level (MRL) simulated blood concentration of each solvent, assuming simultaneous inhalation (24 h/day) and oral ingestion (4 drinking bouts per day) to the measured blood concentration of solvent reported by National Health and Nutrition Examination Survey (NHANES) 2003–2004. The simulated solvent exposure is set to the MRL for inhalation of the solvent in air and ingestion of the solvent in water.

Journal: International Journal of Molecular Sciences

Article Title: Development of a Human Physiologically Based Pharmacokinetic (PBPK) Toolkit for Environmental Pollutants

doi: 10.3390/ijms12117469

Figure Lengend Snippet: Comparison of Minimal Risk Level (MRL) simulated blood concentration of each solvent, assuming simultaneous inhalation (24 h/day) and oral ingestion (4 drinking bouts per day) to the measured blood concentration of solvent reported by National Health and Nutrition Examination Survey (NHANES) 2003–2004. The simulated solvent exposure is set to the MRL for inhalation of the solvent in air and ingestion of the solvent in water.

Article Snippet: The Agency for Toxic Substances and Disease Registry (ATSDR) has conducted translational research to develop a human PBPK model toolkit by recoding published PBPK models.

Techniques: Comparison, Concentration Assay, Solvent